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Proteomics · Acute-Phase Inflammatory Protein — Salivary Analysis

C-reactive protein

C-reactive protein (CRP) is the prototypical hepatic acute-phase reactant, synthesised in response to interleukin-6 and rising with systemic inflammation, infection, and tissue damage. Salivary CRP reflects the magnitude of the post-exercise inflammatory response and cumulative training stress, with elevations signalling incomplete recovery or maladaptation. Wenzel et al. (2026) and Yi et al. (2025) measured salivary CRP among markers of physiological strain and exercise-induced muscle damage.

References

  1. High Frequency Saliva-Based Targeted Multi-Omics as Screening Tool in Professional Soccer — The Practitioner's PerspectiveWenzel C, Kolodziej M, … Zimmer P. · German Journal of Sports Medicine · 2026
  2. Salivary Metabolite Variation After High-Intensity Rowing Training and Potential Biomarker Screening for Exercise-Induced Muscle DamageYi Y, Ding J, Wang B, et al. · Metabolites · 2025 — DOI
  3. Targeted saliva multi-omics is a reliable, non-invasive method to capture physiological stress and recoveryWenzel C, Kalaycik B, … Zimmer P. · TU Dortmund University · 2026